This book, Advances in Aerospace Engineering? Artificial Intelligence, Structures, Materials, and Optimization, explores cutting?edge AI and machine learning methods that are revolutionizing aerospace and aviation. With chapters covering key topics such as AI?driven research, structural analysis using Python, optimization of aircraft design, and the future of high?strength materials like borophene, the book provides insights into how recent advancements contribute to efficiency, sustainability, and innovation in the industry. From energy?efficient UAV routing to sustainable aviation fuels, each chapter offers valuable applications and advanced techniques, making this a comprehensive guide for professionals and researchers in aerospace engineering and AI.